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First published on May 28, 2008, doi:10.1177/1533317508317817

American Journal of Alzheimer's Disease and Other Dementias® 2008;23:262.

A more recent version of this article appeared on June 1, 2008

Article

Consensus Statement on Genetic Research in Dementia

Marcel G. M. Olde Rikkert*, Anco van der Vorm, Alistair Burns, Wim Dekkers, Philipp Robert, Norman Sartorius, Jacques Selmes, Gabriela Stoppe, Myrra Vernooij-Dassen, and Gunhild Waldemar

* To whom correspondence should be addressed. E-mail: M.Olde-Rikkert{at}ger.umcn.nl.


  Abstract
In this article, the authors describe how the European Dementia Consensus Network developed a consensus on research ethics in dementia, taking into account the questions posed by the era of genetic research and its new research methods. The consensus process started with a Delphi procedure to analyze relevant stakeholders’ positions by describing their statements on the possibilities and limitations of research into genetic determinants of Alzheimer disease and to describe and analyze the moral desirability of genetic research on Alzheimer disease. The conclusions drawn from the Delphi procedure fuelled the development of the consensus statement, which is presented in this paper. The consensus statement aims to stimulate ethically acceptable research in the field of dementia and the protection of vulnerable elderly patients with dementia from application of inadequate research methods or designs.


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